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Thefirst group of 15to 60 amino acids on the amino-terminus of a newlysynthesized polypeptide forms a signal sequence(signal peptide) that directs protein to its destination(i.e., lumen of rER).The signal peptide interacts with asignal recognition particle (SRP), which arrests furthergrowth of the polypeptide chain until its relocationtoward the rER membrane. Rarely,oocytes are released from other follicles that have reached fullmaturity during the same cycle, leading to the possibility ofmultiple zygotes. The cervical mucus atother times in the cycle restricts the passage ofsperm into theuterus

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